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Narcoleptic Dogs

Center for Narcolepsy: "Download* a movie of various narcoleptic episodes in both human and animals. Note that both sporadic, dogs and human patients are hypocretin/orexin deficient. The early onset case was found to have a mutation in the preprohypocretin gene. Familial canine narcolepsy are due to mutations in the hypocretin receptor2 genes.

Download* a movie of a 3 year old narcoleptic weimaraner with hypocretin deficiency.

Download* a movie of a narcoleptic mice. The mice model is a preprohypocretin knockout mice (courtesy of Dr. Yanagisawa, Texas, USA, 14Mb)

Download* a movie of a narcoleptic Doberman (Hypocretin receptor-2 mutation) and a narcoleptic Dachshund (sporadic hypocretin deficient dog) (34 Mb) "

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